Can Discord Domain-Containing Receptor 2 Mutation Act as a Disease Modifier for PRKAR1A Associated Melanotic Schwannoma?

Melanotic Schwannomas are rare neural sheath tumors with distinctive findings of both Schwann cells and melanocytic cells.Recognition of this entity has prompted the importance of distinction from similar tumor types such as melanomas.Early diagnosis facilitates removal of the mass with less risk click here of local invasion and metastasis.Although previously known as mostly benign lesions, malignant conversion and recurrence are recognized.This paper presents a patient with melanotic schwannoma, ucsb gaucho blue describes the distinctive features that will separate it from melanoma, and addresses the possibility of further guided therapy through next-generation sequencing.

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